Linked Life Data

7917425

Source:http://linkedlifedata.com/resource/pubmed/id/7917425

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1994-11-10
pubmed:abstractText
An unusual mechanism of metal resistance is found in certain plant pathogenic strains of Pseudomonas syringae that are exposed to high levels of copper compounds used in disease control on agricultural crops. These bacteria accumulate blue Cu2+ ions in the periplasm and outer membrane. At least part of this copper sequestering activity is determined by copper-binding protein products of the copper resistance operon (cop). Potential copper-binding sites of the periplasmic CopA protein show conservation with type-1, type-2, and type-3 copper sites of several eukaryotic multi-copper oxidases. In addition to compartmentalization of copper in the periplasm, two components of the cop operon, copC and copD, appear to function in copper uptake into the cytoplasm. Copper resistance operons related to cop have been described in the related plant pathogen Xanthomonas campestris and in Escherichia coli, but these resistance systems may differ functionally from the Pseudomonas syringae system.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0168-6445
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
381-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Molecular mechanisms of copper resistance and accumulation in bacteria.
pubmed:affiliation
Department of Plant Pathology, University of California, Riverside 92521-0122.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Review, Research Support, Non-U.S. Gov't