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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
|
pubmed:dateCreated |
1994-11-23
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pubmed:abstractText |
A patient with recurrent respiratory papillomatosis progressed spontaneously to carcinoma resulting in death. Serial biopsy specimens obtained during a 9-year course of this patient's disease were tested via polymerase-chain reaction and Southern hybridization to detect the human papillomavirus (HPV) types present during the patient's course of disease. Early biopsy specimens were positive for HPV types 6 and 11. As atypia progressed to carcinoma, HPV types 6 and 11 remained present, but the signal decreased and HPV 16 became increasingly positive. The significance of these findings will be discussed.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0886-4470
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
120
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1273-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7917213-Carcinoma, Squamous Cell,
pubmed-meshheading:7917213-Cell Transformation, Neoplastic,
pubmed-meshheading:7917213-Child, Preschool,
pubmed-meshheading:7917213-Follow-Up Studies,
pubmed-meshheading:7917213-Humans,
pubmed-meshheading:7917213-Laryngeal Neoplasms,
pubmed-meshheading:7917213-Male,
pubmed-meshheading:7917213-Neoplasm Recurrence, Local,
pubmed-meshheading:7917213-Papilloma,
pubmed-meshheading:7917213-Papillomaviridae,
pubmed-meshheading:7917213-Papillomavirus Infections,
pubmed-meshheading:7917213-Polymerase Chain Reaction,
pubmed-meshheading:7917213-Tumor Virus Infections
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pubmed:year |
1994
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pubmed:articleTitle |
Changes in human papillomavirus typing of recurrent respiratory papillomatosis progressing to malignant neoplasm.
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pubmed:affiliation |
Department of Otolaryngology-Head and Neck Surgery, Tulane Medical School, New Orleans, La.
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pubmed:publicationType |
Journal Article,
Case Reports
|