rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1994-8-24
|
pubmed:abstractText |
Intraarterial hepatic (IAH) administration of verapamil should achieve mdr-1-reversing concentrations with reduced cardiac toxicity. The authors have explored the tolerance of its IAH administration and its effects on doxorubicin pharmacodymamics.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0008-543X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
74
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
810-6
|
pubmed:dateRevised |
2010-3-24
|
pubmed:meshHeading |
pubmed-meshheading:7913658-Animals,
pubmed-meshheading:7913658-Carrier Proteins,
pubmed-meshheading:7913658-Doxorubicin,
pubmed-meshheading:7913658-Drug Tolerance,
pubmed-meshheading:7913658-Female,
pubmed-meshheading:7913658-Heart Rate,
pubmed-meshheading:7913658-Hepatic Artery,
pubmed-meshheading:7913658-Infusions, Intra-Arterial,
pubmed-meshheading:7913658-Injections, Intravenous,
pubmed-meshheading:7913658-Liver,
pubmed-meshheading:7913658-Liver Circulation,
pubmed-meshheading:7913658-Liver Neoplasms, Experimental,
pubmed-meshheading:7913658-Membrane Glycoproteins,
pubmed-meshheading:7913658-Neoplasm Transplantation,
pubmed-meshheading:7913658-P-Glycoprotein,
pubmed-meshheading:7913658-Rabbits,
pubmed-meshheading:7913658-Verapamil
|
pubmed:year |
1994
|
pubmed:articleTitle |
Verapamil-reversing concentrations induce blood flow changes that could counteract in vivo the MDR-1-modulating effects.
|
pubmed:affiliation |
Département de Médecine, Institut Gustave-Roussy, Villejuif, France.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|