Linked Life Data

7913077

Source:http://linkedlifedata.com/resource/pubmed/id/7913077

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-8-11
pubmed:abstractText
Results of an epidemiological survey for beta-thalassemic defects involving 239 chromosomes in Algeria are analyzed in relation to the geographic and historical background of the country and are compared with published series for the Tunisian population. Four common mutations account for 81% of the chromosomes, but 13 other defects have been found, illustrating the highly heterogeneous nature of the disease in the northern African countries of the Maghreb. The high frequency of homozygous cases reflects the endogamous social structure of these populations. Distribution of the mutations and linkage to specific RFLP haplotypes provide information concerning their origin and date of introduction in good correlation with the anthropological history of Algeria.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0018-7143
pubmed:author
pubmed:issnType
Print
pubmed:volume
66
pubmed:geneSymbol
beta-globin
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
369-82
pubmed:dateRevised
2011-4-18
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Anthropological approach to the heterogeneity of beta-thalassemia mutations in northern Africa.
pubmed:affiliation
Centre de Transfusion Sanguine, Hôpital Mustapha, Alger, Algeria.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't