Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1994-7-27
pubmed:abstractText
A novel method of pancreatic anastomosis after proximal Whipple-type resection: classical pancreaticoduodenectomy (PD) or pylorus-preserving pancreaticoduodenectomy (PPPD), has been evaluated over a 5-year period from 1987 to 1992 in 52 patients. Indications for resection included chronic pancreatitis (n = 9) and neoplasms (n = 43). Reconstruction involved a cephalad end-to-end duodeno-/gastro-jejunal anastomosis with a biliary anastomosis 6-8 cm downstream. A separate isolated defunctioned Roux loop was used to construct a duct-to-mucosa (Wirsung-jejunal) pancreaticojejunostomy. Median postoperative stay was 18.0 days (range 11-32 days); three deaths (operative mortality 5.8%) occurred due to sepsis (subhepatic abscess), profound hypoglycaemia and necrotising pancreatitis respectively. These deaths were not related to pancreatic fistula. There were no pancreatic leaks (defined as greater than 50 ml of amylase-rich fluid for more than 7 days). Postoperative exocrine pancreatic function was good as assessed by re-establishment of preoperative weight (achieved in 35 of 40, ie 88% of surviving PPPD patients), clinical steatorrhoea (present in 10 of 41, ie 24% of surviving patients resected for neoplasm), and the need for pancreatic exocrine supplements (required in only 4 of 41, ie 9.8% of surviving patients resected for neoplasm). Twenty patients considered to have normal pancreatic remnants underwent a p-aminobenzoic acid (PABA) excretion test at 3 to 18 months after operation. Median PABA excretion index was 48% (range 24-100%). Isolated defunctioned duct-to-mucosa pancreaticojejunostomy is a safe procedure offering good functional results after Whipple's PD or PPPD resection.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1015887, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1345762, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1346946, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1353751, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1575313, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1681888, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1685076, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1732772, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-17856666, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-17857895, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-17857897, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-1987857, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-2034005, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-2302521, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-2322039, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-2742478, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-2814757, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-2917265, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-3276272, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-3314748, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-3382346, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-3566523, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-3589910, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-3652794, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-3742181, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-3767476, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-4823372, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-5680953, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-6623327, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-6712319, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-6791804, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-6874316, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-7388307, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-779079, http://linkedlifedata.com/resource/pubmed/commentcorrection/7912489-8093656
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0035-8843
pubmed:author
pubmed:issnType
Print
pubmed:volume
76
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
175-9
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed-meshheading:7912489-Adult, pubmed-meshheading:7912489-Aged, pubmed-meshheading:7912489-Anastomosis, Surgical, pubmed-meshheading:7912489-Chronic Disease, pubmed-meshheading:7912489-Duodenum, pubmed-meshheading:7912489-Evaluation Studies as Topic, pubmed-meshheading:7912489-Female, pubmed-meshheading:7912489-Humans, pubmed-meshheading:7912489-Jejunum, pubmed-meshheading:7912489-Length of Stay, pubmed-meshheading:7912489-Male, pubmed-meshheading:7912489-Middle Aged, pubmed-meshheading:7912489-Pancreas, pubmed-meshheading:7912489-Pancreatic Fistula, pubmed-meshheading:7912489-Pancreatic Neoplasms, pubmed-meshheading:7912489-Pancreaticoduodenectomy, pubmed-meshheading:7912489-Pancreaticojejunostomy, pubmed-meshheading:7912489-Pancreatitis, pubmed-meshheading:7912489-Postoperative Complications, pubmed-meshheading:7912489-Safety, pubmed-meshheading:7912489-Stomach
pubmed:year
1994
pubmed:articleTitle
Safety and function of isolated Roux loop pancreaticojejunostomy after Whipple's pancreaticoduodenectomy.
pubmed:affiliation
Department of Surgery, University of Liverpool.
pubmed:publicationType
Journal Article