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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1994-7-18
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pubmed:abstractText |
Hairy cell leukemia is a rare chronic B-lymphocyte malignancy characterized by pancytopenia, splenomegaly, immunological abnormalities and morphologically typical neoplastic mononuclear cells in blood and bone marrow. Until recently the disorder was treated with splenectomia and/or alpha-interferon. Intravenous infusion of 2-chloro-deoxy-adenosine (2-CdA) is a new and efficacious treatment principle making hairy cell leukemia a potentially curable disease. A Nordic cooperative study is currently examining the effects of 2-CdA given subcutaneously for seven days. 19 Norwegian patients are included so far, with encouraging results. The long-term effect of 2-CdA is not yet known. The high remission frequency, the short duration of the treatment and the few side effects make this drug a natural first choice in treating hairy cell leukemia.
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pubmed:language |
nor
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0029-2001
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
114
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
800-3
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pubmed:dateRevised |
2008-7-16
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pubmed:meshHeading |
pubmed-meshheading:7912011-Adult,
pubmed-meshheading:7912011-Aged,
pubmed-meshheading:7912011-Cladribine,
pubmed-meshheading:7912011-Female,
pubmed-meshheading:7912011-Humans,
pubmed-meshheading:7912011-Injections, Subcutaneous,
pubmed-meshheading:7912011-Leukemia, Hairy Cell,
pubmed-meshheading:7912011-Male,
pubmed-meshheading:7912011-Middle Aged,
pubmed-meshheading:7912011-Prognosis,
pubmed-meshheading:7912011-Time Factors
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pubmed:year |
1994
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pubmed:articleTitle |
[Progress in the treatment of hairy cell leukemia. Subcutaneous administration of 2-chloro-deoxy-adenosine for 7 days].
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pubmed:affiliation |
Hematologisk seksjon, Medisinsk avdeling A, Rikshospitalet, Oslo.
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
|