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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1994-4-1
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pubmed:abstractText |
The NAT2 gene encodes for a polymorphic arylalkylamine N-acetyltransferase and thus accounts for the human N-acetylation polymorphism. By a NAT2-specific primer set we have screened a human chromosome 8-specific cosmid library. A positive cosmid clone was mapped by fluorescence in situ hybridization to 8p22. The polymerase chain reaction followed by restriction analysis of the PCR product was used to identify allele 2 to be contained in the cosmid clone.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-291X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
28
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pubmed:volume |
199
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pubmed:geneSymbol |
NAT2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
52-5
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pubmed:dateRevised |
2010-9-8
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pubmed:meshHeading |
pubmed-meshheading:7907215-Arylamine N-Acetyltransferase,
pubmed-meshheading:7907215-Base Sequence,
pubmed-meshheading:7907215-Chromosome Mapping,
pubmed-meshheading:7907215-Chromosomes, Human, Pair 8,
pubmed-meshheading:7907215-Cloning, Molecular,
pubmed-meshheading:7907215-Cosmids,
pubmed-meshheading:7907215-DNA Primers,
pubmed-meshheading:7907215-Humans,
pubmed-meshheading:7907215-In Situ Hybridization, Fluorescence,
pubmed-meshheading:7907215-Molecular Sequence Data,
pubmed-meshheading:7907215-Polymorphism, Restriction Fragment Length
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pubmed:year |
1994
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pubmed:articleTitle |
Isolation and mapping of a cosmid clone containing the human NAT2 gene.
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pubmed:affiliation |
Center for Human Genetics and Genetic Counselling, University of Bremen, Germany.
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pubmed:publicationType |
Journal Article
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