pubmed-article:7904822 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:7904822 | lifeskim:mentions | umls-concept:C0927232 | lld:lifeskim |
pubmed-article:7904822 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
pubmed-article:7904822 | lifeskim:mentions | umls-concept:C0040845 | lld:lifeskim |
pubmed-article:7904822 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
pubmed-article:7904822 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
pubmed-article:7904822 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
pubmed-article:7904822 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
pubmed-article:7904822 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:7904822 | pubmed:dateCreated | 1994-3-1 | lld:pubmed |
pubmed-article:7904822 | pubmed:abstractText | The identification and molecular characterization of Brn-3.2 has revealed a family of Brn-3-related mammalian POU proteins that share homology with the C. elegans developmental regulator Unc-86 and extended similarity with the Drosophila neurodevelopmental gene I-POU, which defines a novel POU-IV box. Brn-3.2 exhibits DNA binding properties similar to those of Brn-3.0, but its expression is uniquely regulated by retinoic acid in teratocarcinoma and neuroblastoma cells. In the developing PNS and retina, the expression pattern of Brn-3.2 is similar to that of Brn-3.0. In the caudal CNS (spinal cord, hindbrain, and midbrain) Brn-3.2 and Brn-3.0 are initially coexpressed, but diverge later in development. Rostral to the midbrain, Brn-3.2 and Brn-3.0 exhibit nonoverlapping patterns of expression, suggesting divergence of gene function in more recently evolved structures. Our analysis suggests that in the CNS Brn-3.2 is selectively expressed in postmitotic neurons, implying a role in specifying terminally differentiated neuronal phenotypes. | lld:pubmed |
pubmed-article:7904822 | pubmed:language | eng | lld:pubmed |
pubmed-article:7904822 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:7904822 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:7904822 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:7904822 | pubmed:month | Jan | lld:pubmed |
pubmed-article:7904822 | pubmed:issn | 0896-6273 | lld:pubmed |
pubmed-article:7904822 | pubmed:author | pubmed-author:RosenfeldM... | lld:pubmed |
pubmed-article:7904822 | pubmed:author | pubmed-author:TurnerE EEE | lld:pubmed |
pubmed-article:7904822 | pubmed:author | pubmed-author:JenneK JKJ | lld:pubmed |
pubmed-article:7904822 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:7904822 | pubmed:volume | 12 | lld:pubmed |
pubmed-article:7904822 | pubmed:geneSymbol | Brn-3.0 | lld:pubmed |
pubmed-article:7904822 | pubmed:geneSymbol | Brn-3.2 | lld:pubmed |
pubmed-article:7904822 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:7904822 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:7904822 | pubmed:pagination | 205-18 | lld:pubmed |
pubmed-article:7904822 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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pubmed-article:7904822 | pubmed:year | 1994 | lld:pubmed |
pubmed-article:7904822 | pubmed:articleTitle | Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid. | lld:pubmed |
pubmed-article:7904822 | pubmed:affiliation | Howard Hughes Medical Institute, Eukaryotic Regulatory Biology Program, University of California, San Diego. | lld:pubmed |
pubmed-article:7904822 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:7904822 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:7904822 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:7904822 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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