Linked Life Data

7903986

Source:http://linkedlifedata.com/resource/pubmed/id/7903986

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1994-2-4
pubmed:abstractText
Many drugs have been known to cause movement disorders with different mechanisms of action. Most of these drugs interfere with dopaminergic transmission within the basal ganglia. However, numerous other drugs are capable of producing movement disorders, whose mechanism is not at all clearly understood. Neuroleptic drugs-induced extrapyramidal symptoms such as dystonia, akathisia, parkinsonism have been related to sudden imbalance between the striatal dopamine and cholinergic systems, causing a relative preponderance of acetylcholine. Some calcium channel blockers and H2 blockers induced or aggravated parkinsonism and other extrapyramidal symptoms. It has been suggested that calcium channel blockers-induced extrapyramidal symptoms are much more common in elderly patients. In H2 blockers induced movement disorders, renal and liver dysfunction is the risk factor of them, but the mechanism is not clearly understood.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0047-1852
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2929-34
pubmed:dateRevised
2011-7-27
pubmed:meshHeading
pubmed:year
1993
pubmed:articleTitle
[Drug-induced movement disorders].
pubmed:affiliation
Department of Psychiatry, Kitasato University School of Medicine.
pubmed:publicationType
Journal Article, English Abstract, Review