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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5138
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pubmed:dateCreated |
1993-12-23
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pubmed:databankReference |
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pubmed:abstractText |
The Pto gene in tomato confers resistance to races of Pseudomonas syringae pv. tomato that carry the avirulence gene avrPto. A yeast artificial chromosome clone that spans the Pto region was identified and used to probe a leaf complementary DNA (cDNA) library. A cDNA clone was isolated that represents a gene family, at least six members of which genetically cosegregate with Pto. When susceptible tomato plants were transformed with a cDNA from this family, they were resistant to the pathogen. Analysis of the amino acid sequence revealed similarity to serine-threonine protein kinases, suggesting a role for Pto in a signal transduction pathway.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0036-8075
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
262
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pubmed:geneSymbol |
Pto
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1432-6
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:7902614-Amino Acid Sequence,
pubmed-meshheading:7902614-Chromosomes, Artificial, Yeast,
pubmed-meshheading:7902614-Cloning, Molecular,
pubmed-meshheading:7902614-DNA, Complementary,
pubmed-meshheading:7902614-Genes, Plant,
pubmed-meshheading:7902614-Molecular Sequence Data,
pubmed-meshheading:7902614-Multigene Family,
pubmed-meshheading:7902614-Plant Diseases,
pubmed-meshheading:7902614-Plant Proteins,
pubmed-meshheading:7902614-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:7902614-Protein-Serine-Threonine Kinases,
pubmed-meshheading:7902614-Pseudomonas,
pubmed-meshheading:7902614-Signal Transduction,
pubmed-meshheading:7902614-Vegetables,
pubmed-meshheading:7902614-Virulence
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pubmed:year |
1993
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pubmed:articleTitle |
Map-based cloning of a protein kinase gene conferring disease resistance in tomato.
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pubmed:affiliation |
Department of Plant Breeding and Biometry, Cornell University, Ithaca, NY 14853-1902.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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