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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1993-12-17
|
| pubmed:abstractText |
Congenital arteriovenous malformation (AVM) of the brain represents a defect in capillary development resulting in a high flow fistula between arterial and venous systems. In this study, AVM hemodynamics were related with clinical findings. Volume flow was calculated based on transcranial Doppler (TCD) and angiographic data. Forty patients admitted to the Massachusetts General Hospital for proton beam therapy (33 +/- 10 yr old; mean +/- SD) were studied. Four symptoms were considered: intracranial bleeding, progressive neurological deficit, seizures, and headache. Fourteen control subjects aged 30 +/- 7 years (mean +/- SD) were normal volunteers. Angiography with calibrated markers permitting magnification correction was available for all patients. Lateral and medial depth limits of the intracranial basal arteries in relation to the TCD temporal window were determined by TCD and angiogram with excellent correlation. Selected depth for data acquisition was determined independently in the angiogram and by TCD. The difference between the two techniques was less than 4 mm. Mean flow velocity, pulsatility index, and vessel diameter were studied. Flow volume was calculated from these data. Mean flow velocity, pulsatility index, vessel diameter, and flow volume were significantly different among AVM feeders, non-feeders, and control arteries. The non-feeding middle cerebral artery, anterior cerebral artery, and posterior cerebral artery flows were 254 +/- 13, 136 +/- 14, and 79 +/- 8 ml/min, respectively. Accordingly, the estimated cerebral flow volume was 938 ml/min. The feeding middle cerebral artery, anterior cerebral artery, and posterior cerebral artery flows were 552 +/- 47, 369 +/- 70, and 484 +/- 67 ml/min, respectively (P < 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0148-396X
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
33
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
556-62; discussion 562
|
| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:7901793-Adolescent,
pubmed-meshheading:7901793-Adult,
pubmed-meshheading:7901793-Blood Flow Velocity,
pubmed-meshheading:7901793-Blood Volume,
pubmed-meshheading:7901793-Brain,
pubmed-meshheading:7901793-Cerebral Angiography,
pubmed-meshheading:7901793-Cerebral Hemorrhage,
pubmed-meshheading:7901793-Child,
pubmed-meshheading:7901793-Female,
pubmed-meshheading:7901793-Humans,
pubmed-meshheading:7901793-Intracranial Arteriovenous Malformations,
pubmed-meshheading:7901793-Male,
pubmed-meshheading:7901793-Middle Aged,
pubmed-meshheading:7901793-Neurologic Examination,
pubmed-meshheading:7901793-Protons,
pubmed-meshheading:7901793-Ultrasonography, Doppler, Transcranial
|
| pubmed:year |
1993
|
| pubmed:articleTitle |
Arteriovenous malformation hemodynamics: a transcranial Doppler study.
|
| pubmed:affiliation |
Department of Neurology, Massachusetts General Hospital, Harvard School of Medicine, Boston.
|
| pubmed:publicationType |
Journal Article
|