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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1993-12-2
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pubmed:abstractText |
Four patients with solid tumors were treated with high dose chemotherapy and HLA-mismatched multi-cord blood transplantation. Of them, 3 reached complete remission, 1 got fair response. The side effects were tolerable. Little or no graft-versus-host reaction (GVHR) was observed. Donor cell engraftment was documented in 2 patients by cytogenetic analysis and determination of hemoglobin F of the peripheral blood. Recurrent diseases were confirmed clinically on day 210 (4 year-old girl with liposarcoma) and day 90 (11 year-old boy with non-Hodgkin's lymphoma). These results demonstrated that HLA-mismatched multicord blood transfusion could rescue myelo-suppression of patients treated with myeloablative chemotherapy. Therefore, cord blood may serve as a rich source of hematopoietic stem cells.
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pubmed:language |
chi
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0253-3766
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
152-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7900979-Blood Component Transfusion,
pubmed-meshheading:7900979-Blood Transfusion,
pubmed-meshheading:7900979-Child,
pubmed-meshheading:7900979-Child, Preschool,
pubmed-meshheading:7900979-Female,
pubmed-meshheading:7900979-Fetal Blood,
pubmed-meshheading:7900979-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:7900979-Humans,
pubmed-meshheading:7900979-Liposarcoma,
pubmed-meshheading:7900979-Lymphoma,
pubmed-meshheading:7900979-Male,
pubmed-meshheading:7900979-Neoplasms,
pubmed-meshheading:7900979-Neuroblastoma,
pubmed-meshheading:7900979-Ovarian Neoplasms,
pubmed-meshheading:7900979-Pelvic Neoplasms,
pubmed-meshheading:7900979-Retroperitoneal Neoplasms,
pubmed-meshheading:7900979-Teratoma
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pubmed:year |
1993
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pubmed:articleTitle |
[Human umbilical cord blood transplantation in 4 cases with advanced solid tumors].
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pubmed:affiliation |
Shandong Medical University Hospital, Jinan.
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pubmed:publicationType |
Journal Article,
English Abstract
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