Linked Life Data

7898479

Source:http://linkedlifedata.com/resource/pubmed/id/7898479

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1995-4-27
pubmed:abstractText
We have focused in part on utilizing molecular aspects of the PADPRP gene sequences located on chromosome 1q as well as on 13 to help clarify the biological role of these genes. With respect to chromosome 1q, stably transfected cell lines have been established in-both HeLa as well as 3T3-L1 preadipocyte cells, which express a reverse complementary transcription product in vivo to the exons coded for on the chromosome 1 locus. Also, in the case of the PADPRP-like gene on chromosome 13q, we have fine mapped this sequence and have observed in a linkage of deletion of this region with predisposition to various forms of cancer, especially in the African-American population.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0300-8177
pubmed:author
pubmed:issnType
Print
pubmed:volume
138
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
77-84
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Poly(ADP-ribose) polymerase gene on chromosome 1q: early role in differentiation linked replication; gene on human chromosome 13q: marker of carcinogenesis.
pubmed:affiliation
Georgetown University Medical School, Dept. of Biochemistry and Molecular Biology, Washington, DC 20007.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.