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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1995-4-27
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pubmed:abstractText |
Hereditary multi-infarct dementia is a rare autosomal dominant disorder that predominantly affects the cerebral white matter. A locus was recently mapped in French pedigrees to chromosome 19q12. We have examined a large Scottish pedigree with neuropathologically confirmed hereditary multi-infarct dementia using polymorphic DNA markers spanning the 19q12 region and found no evidence of linkage. This suggests that, as in familial Alzheimer's disease, there is more than one locus.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-1579224,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-1592574,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-1926242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-2651569,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-3324647,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-3435081,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-3678285,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-3859205,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-69080,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-7545953,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-8330881,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-8485581,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7897629-906807
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0022-2593
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57-60
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:7897629-Adult,
pubmed-meshheading:7897629-Aged,
pubmed-meshheading:7897629-Chromosomes, Human, Pair 19,
pubmed-meshheading:7897629-Dementia, Multi-Infarct,
pubmed-meshheading:7897629-Female,
pubmed-meshheading:7897629-Genes, Dominant,
pubmed-meshheading:7897629-Genetic Heterogeneity,
pubmed-meshheading:7897629-Genetic Linkage,
pubmed-meshheading:7897629-Humans,
pubmed-meshheading:7897629-Male,
pubmed-meshheading:7897629-Middle Aged,
pubmed-meshheading:7897629-Pedigree,
pubmed-meshheading:7897629-Scotland
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pubmed:year |
1995
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pubmed:articleTitle |
Hereditary multi-infarct dementia unlinked to chromosome 19q12 in a large Scottish pedigree: evidence of probable locus heterogeneity.
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pubmed:affiliation |
MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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