Linked Life Data

7895779

Source:http://linkedlifedata.com/resource/pubmed/id/7895779

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-4-26
pubmed:abstractText
Autologous stem cell transplantation (ASCT) is a therapeutic approach that permits the administration of high-dose chemoradiotherapy followed by the infusion of the patient's own hemotopoietic cells, previously collected during remission and cryopreserved [1-4]. The long-term outcome of ASCT is mainly affected by relapse of the underlying disease that represents the major cause of failure of ASCT. The contribution of reinfused tumor cells to relapse is suggested by several clinical studies and has been recently demonstrated by autografting genetically marked cells. In this minireview, advantages and limitations of currently available purging techniques will be analyzed. In addition, the potential clinical implications of new technological approaches for purging will be discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0301-472X
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
296-302
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Stem cell purging: an intriguing dilemma.
pubmed:affiliation
Department of Hematology, University of Parma, Italy.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't