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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1995-4-24
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pubmed:abstractText |
Electrically coupled pairs of cultured rat glomus cells were used. In one group of experiments, both cells were current-clamped. Delivery of positive or negative pulses to Cell 1 elicited appreciable voltage noise in this cell and large action potentials (probably Ca2+ spikes) in about 10% of them. Both passive and active electrical events spread to Cell 2, presumably through the gap junctions between them. The coupling coefficient (Kc) was larger for the spikes than for non-regenerative voltage noise. In another group of experiments, Cell 1 was current-clamped and Cell 2 was voltage-clamped at Cell 1 EM. Pulses of either polarity, delivered to Cell 1, produced current flow through the intercellular junction and allowed direct measurements of junctional currents (Ij) and total conductances (Gj). Ij had a mean value of about 12.5 pA and Gj of 391 pS. Unitary (presumably single channel) conductance (gj) was about 78 pS.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
664
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-65
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7895039-Action Potentials,
pubmed-meshheading:7895039-Animals,
pubmed-meshheading:7895039-Carotid Body,
pubmed-meshheading:7895039-Cell Communication,
pubmed-meshheading:7895039-Cells, Cultured,
pubmed-meshheading:7895039-Electric Conductivity,
pubmed-meshheading:7895039-Electric Stimulation,
pubmed-meshheading:7895039-Gap Junctions,
pubmed-meshheading:7895039-Membrane Potentials,
pubmed-meshheading:7895039-Rats,
pubmed-meshheading:7895039-Rats, Wistar
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pubmed:year |
1994
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pubmed:articleTitle |
Electrical coupling between cultured glomus cells of the rat carotid body: observations with current and voltage clamping.
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pubmed:affiliation |
Department of Physiology, University of Utah School of Medicine, Salt Lake City 84108.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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