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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1995-4-24
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pubmed:abstractText |
In this prospective study, we evaluated the predictive value of activated partial thromboplastin time on day 8 post transplantation for event-free survival in patients who had had orthotopic liver transplants; both death and retransplantation within 6 months were the events considered. In a 4-year period, 109 patients had orthotopic liver transplants in our hospital, and 104 were eligible for the study since they survived and were not given new transplants within 8 days. The activated partial thromboplastin time was significantly longer in patients who survived event-free for less than 6 months than in those with longer event-free survivals. Kaplan-Meier curves showed that patients with normal activated partial thromboplastin times were nine times more likely to survive more than 6 months without events than patients with prolonged values. The positive predictive value of activated partial thromboplastin time for event-free survival was 88% and the negative predictive value was 54%, indicating that the test is useful for predicting patient outcome. We suggest that activated partial thromboplastin time be performed on day 8 post transplantation to predict the medium-term event-free survival.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0940-5437
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
220-2
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7894048-Adolescent,
pubmed-meshheading:7894048-Adult,
pubmed-meshheading:7894048-Child,
pubmed-meshheading:7894048-Child, Preschool,
pubmed-meshheading:7894048-Female,
pubmed-meshheading:7894048-Humans,
pubmed-meshheading:7894048-Infant,
pubmed-meshheading:7894048-Liver Transplantation,
pubmed-meshheading:7894048-Male,
pubmed-meshheading:7894048-Middle Aged,
pubmed-meshheading:7894048-Partial Thromboplastin Time,
pubmed-meshheading:7894048-Predictive Value of Tests,
pubmed-meshheading:7894048-Prognosis,
pubmed-meshheading:7894048-Prospective Studies,
pubmed-meshheading:7894048-Survival Rate
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pubmed:year |
1994
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pubmed:articleTitle |
Prognostic value of the activated partial thromboplastin time after orthotopic liver transplantation. A prospective study.
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pubmed:affiliation |
Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Institute of Internal Medicine, Milan, Italy.
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pubmed:publicationType |
Journal Article
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