| pubmed-article:789272 | pubmed:abstractText | Liquid-holding treatment in non-nutrient solutions after U.V.-exposure results in an increased resistance of wild-type (RAD) yeast cells to a second U.V.-treatment (repair resistance). U.V.-sensitive (rad) mutants of yeast which show variation in their response to liquid-holding treatment and a second U.V.-dose-range have been classified into two groups. Mutants of Group 1 show increased viability after post-U.V.-liquid-holding treatment and show repair resistance. In contrast, mutants of Group 2 which show reduced viability during post-U.V.-liquid-holding treatment have the same U.V.-sensitivity, both before and after liquid-holding treatment. Genetic analysis of crosses of the rad mutants to wild-type cultures indicate that the phenotype of repair resistance to U.V.-treatment is under genetic control and depends on the presence of alleles of radiation sensitivity genes, which also confer the property of liquid-holding recovery. | lld:pubmed |
