Linked Life Data

789173

Source:http://linkedlifedata.com/resource/pubmed/id/789173

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1976-12-30
pubmed:abstractText
Twelve histamines have been so far identified in living animal tissues. The two reactive sites of the histamine molecule involved in the production of these derivatives are represented by the imino nitrogen of the nucleus and the amino group of the lateral chain. The ring imino nitrogen may be methylated, to form 3-methylhistamine, or conjugated with ribose to give origin to histamine riboside, ribotide and dinucleotide. The amino group of thelateral chain, in its turn, may be methylated (N'-methyl-histamine, N',N'-dimethylhistamine), conjugated with aliphatic acids (N'-imidazoleproprionylhistamine, N'-urocanylhistamine) or amino acids (beta-alanylhistamine or carcinine), and finally linked, through a methyl group, to the imidazole nucleus to give origin to imidazo-c-pyridine derivatives or cyclized histamines. The biosynthesis of the above natural histamines and their physiological significance are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0306-3623
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
221-5
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Natural histamines.
pubmed:publicationType
Journal Article, Review