rdf:type |
|
lifeskim:mentions |
umls-concept:C0006556,
umls-concept:C0009015,
umls-concept:C0017262,
umls-concept:C0023884,
umls-concept:C0034493,
umls-concept:C0185117,
umls-concept:C0679058,
umls-concept:C1413154,
umls-concept:C1547699,
umls-concept:C2700640,
umls-concept:C2911684
|
pubmed:issue |
2
|
pubmed:dateCreated |
1995-4-20
|
pubmed:databankReference |
|
pubmed:abstractText |
Two cDNA sequences encoding rabbit carbonyl reductase (CBR) were cloned from a lambda gt10 rabbit liver cDNA library. The rabbit cDNAs coded for a protein with 84% identity to human CBR. Transient expression of the two rabbit cDNA sequences in COS7 cells increased both quinone reductase and aldo-keto reductase activities. These data demonstrate that CBR cDNAs from rabbit and human tissues code for similar proteins.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0378-1119
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
10
|
pubmed:volume |
154
|
pubmed:geneSymbol |
RCBR5,
RCBR6
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
297-8
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7890182-Alcohol Oxidoreductases,
pubmed-meshheading:7890182-Amino Acid Sequence,
pubmed-meshheading:7890182-Animals,
pubmed-meshheading:7890182-Base Sequence,
pubmed-meshheading:7890182-Cells, Cultured,
pubmed-meshheading:7890182-Cercopithecus aethiops,
pubmed-meshheading:7890182-Cloning, Molecular,
pubmed-meshheading:7890182-DNA, Complementary,
pubmed-meshheading:7890182-Genes,
pubmed-meshheading:7890182-Humans,
pubmed-meshheading:7890182-Liver,
pubmed-meshheading:7890182-Molecular Sequence Data,
pubmed-meshheading:7890182-NAD(P)H Dehydrogenase (Quinone),
pubmed-meshheading:7890182-RNA, Messenger,
pubmed-meshheading:7890182-Rabbits,
pubmed-meshheading:7890182-Sequence Alignment,
pubmed-meshheading:7890182-Sequence Analysis, DNA
|
pubmed:year |
1995
|
pubmed:articleTitle |
Cloning and expression of the cDNA encoding rabbit liver carbonyl reductase.
|
pubmed:affiliation |
Division of Biology, Beckman Research Institute, City of Hope, Duarte, CA 91010, USA.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
|