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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1995-4-20
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pubmed:abstractText |
T-cell prolymphocytic leukaemia (T-PLL) is an aggressive leukaemia accounting for over 30% of all mature T-cell malignancies. We describe the clinical manifestations and histology of cutaneous involvement in a series of 92 patients with T-PLL. Of the 92 patients, 26 (28%) had cutaneous involvement, and in 23 this was present at the time of the diagnosis of the leukaemia. Skin manifestations included a diffuse infiltrated erythema, infiltration localized to the face and ears, nodules and erythroderma. Histology showed a perivascular and periappendageal dermal infiltrate of lymphoid cells with the morphology of prolymphocytes. An early skin biopsy in these patients should help to reveal the underlying diagnosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0007-0963
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
132
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
263-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7888364-Adult,
pubmed-meshheading:7888364-Aged,
pubmed-meshheading:7888364-Aged, 80 and over,
pubmed-meshheading:7888364-Erythema,
pubmed-meshheading:7888364-Female,
pubmed-meshheading:7888364-Humans,
pubmed-meshheading:7888364-Leukemia, Prolymphocytic,
pubmed-meshheading:7888364-Leukemia, T-Cell,
pubmed-meshheading:7888364-Leukemic Infiltration,
pubmed-meshheading:7888364-Male,
pubmed-meshheading:7888364-Middle Aged,
pubmed-meshheading:7888364-Skin
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pubmed:year |
1995
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pubmed:articleTitle |
Cutaneous infiltration in T-cell prolymphocytic leukaemia.
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pubmed:affiliation |
Department of Dermatology, St Helier NHS Trust, Carshalton, Surrey, U.K.
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pubmed:publicationType |
Journal Article
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