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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1995-4-12
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pubmed:abstractText |
Serum humoral immune response to Cryptosporidium parvum was evaluated in six species: mouse, rabbit, lamb, calf, pig and man. Electrophoretic and immunoblot analysis showed that specific animal antibody response appeared between Day 4 and Day 15 post inoculation. The two main target antigens had apparent molecular weights of 15-17 and 23 kDa. They were recognised by each species studied. Serum IgA intensively recognised the 15-17 kDa antigen, except in rabbit. This study demonstrates that these two antigens are consistent targets of humoral immune response and can therefore be of great interest in studies of therapy/prophylaxis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0304-4017
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-13
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7886907-Animals,
pubmed-meshheading:7886907-Antibodies, Monoclonal,
pubmed-meshheading:7886907-Antibodies, Protozoan,
pubmed-meshheading:7886907-Antibody Formation,
pubmed-meshheading:7886907-Antigens, Protozoan,
pubmed-meshheading:7886907-Blotting, Western,
pubmed-meshheading:7886907-Cattle,
pubmed-meshheading:7886907-Child,
pubmed-meshheading:7886907-Cryptosporidiosis,
pubmed-meshheading:7886907-Cryptosporidium parvum,
pubmed-meshheading:7886907-Humans,
pubmed-meshheading:7886907-Immunoglobulin G,
pubmed-meshheading:7886907-Immunoglobulin M,
pubmed-meshheading:7886907-Mice,
pubmed-meshheading:7886907-Mice, Inbred BALB C,
pubmed-meshheading:7886907-Rabbits,
pubmed-meshheading:7886907-Sheep,
pubmed-meshheading:7886907-Species Specificity,
pubmed-meshheading:7886907-Swine
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pubmed:year |
1994
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pubmed:articleTitle |
Major antigens of Cryptosporidium parvum recognised by serum antibodies from different infected animal species and man.
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pubmed:affiliation |
Unité de Recherche Université-INRA d'Immunologie Parasitaire, UFR des Sciences Pharmaceutiques, Centre INRA de Tours, Nouzilly, France.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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