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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1995-4-13
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pubmed:abstractText |
Hemostatic profiles and cardiac enzymes were studied in 55 acute myocardial infarct (AMI) patients to assess SK and rt-PA therapy. Hypofibrinogenemia occurred 85% in SK group and 55% in rt-PA group with high FDP and D-Dimer, indicating systemic fibrinogenolysis and local crosslinked fibrin clot lysis. The incidence of bleeding in SK and rt-PA groups combined with anticoagulants were the same but lower in rt-PA with antiplatelet. The mean FDP was significantly higher in the bleeding group (p < 0.01). Cardiac enzymes: CK, CK-MB peak values indicated reperfusion were 26.6%, 60% and 90% in conventional, SK and rt-PA therapy, respectively. Early and late occlusion did not occur either in SK or rt-PA followed by anticoagulants. Late occlusion was found in patients treated with rt-PA and antiplatelet. Mortality rate was 20% in conventional therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Dipyridamole,
http://linkedlifedata.com/resource/pubmed/chemical/Heparin,
http://linkedlifedata.com/resource/pubmed/chemical/Streptokinase,
http://linkedlifedata.com/resource/pubmed/chemical/Tissue Plasminogen Activator,
http://linkedlifedata.com/resource/pubmed/chemical/Warfarin
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pubmed:status |
MEDLINE
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pubmed:issn |
0125-1562
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
144-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7886558-Blood Coagulation Disorders,
pubmed-meshheading:7886558-Blood Coagulation Tests,
pubmed-meshheading:7886558-Dipyridamole,
pubmed-meshheading:7886558-Drug Monitoring,
pubmed-meshheading:7886558-Drug Therapy, Combination,
pubmed-meshheading:7886558-Female,
pubmed-meshheading:7886558-Heparin,
pubmed-meshheading:7886558-Humans,
pubmed-meshheading:7886558-Male,
pubmed-meshheading:7886558-Myocardial Infarction,
pubmed-meshheading:7886558-Streptokinase,
pubmed-meshheading:7886558-Tissue Plasminogen Activator,
pubmed-meshheading:7886558-Warfarin
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pubmed:year |
1993
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pubmed:articleTitle |
Laboratory assessment of thrombolytic therapy in acute myocardial infarction.
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pubmed:affiliation |
Department of Clinical Pathology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial,
Research Support, Non-U.S. Gov't
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