Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1995-4-12
pubmed:abstractText
A mix of peptides and amino acids obtained from porcine brain tissue (Cerebrolysin) has been shown to affect passive avoidance behavior in neonatal rats. To identify the active components and mechanisms of action, Cerebrolysin effects were studied in in vitro hippocampal slices. Cerebrolysin induced dose-dependent suppression followed by a small rebound increase of synaptic responses in the CA1 but not dentate gyrus neurons. These actions may be due to peptides present in Cerebrolysin and may contribute to its reported behavioural effects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0091-3057
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1105-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Effects of brain tissue hydrolysate on synaptic transmission in the hippocampus.
pubmed:affiliation
Department of Physiology, University of Toronto, Ontario, Canada.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't