Linked Life Data

7885021

Source:http://linkedlifedata.com/resource/pubmed/id/7885021

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-4-13
pubmed:abstractText
The effects of long-chain triglycerides (LCT) and of medium-chain triglycerides (MCT) on intestinal adaptation in rats were compared following a 60% resection of intestine. Sixty Long-Evans rats were divided into four groups: control (sham-operated) rats fed an MCT-enriched diet, control rats fed an LCT-enriched diet, experimental rats fed an MCT-enriched diet, and experimental rats fed an LCT-enriched diet. In the MCT-enriched diet, 90% of the fat was MCT; in the LCT diet, 90% was LCT. In each diet, 31-32% of daily caloric intake came from fat. All diets were isocaloric and isonitrogenous. Following the 60% intestinal resection from the mid-portion of the small intestine, there were significant increases in mucosal height, villous height, villous width, and crypt depth (P < 0.05). Gut weight, mucosal weight, protein and DNA content, and DNA synthetic rate also increased. In the ileum, rats receiving the LCT diet showed greater increases in gut weight, mucosal weight, crypt depth, protein and DNA content, and DNA synthetic rate than the MCT rats did (P < 0.05). In the jejunum, however, the differences were not statistically significant. In both the jejunum and the ileum, the response of the intestine was greater closer to the anastomotic site (P < 0.05). Results of these studies demonstrated that LCT had a better effect than MCT on intestinal response both structurally and functionally.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-4804
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
253-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
Effects of lipids on intestinal adaptation following 60% resection in rats.
pubmed:affiliation
Department of Surgery, College of Medicine, National Taiwan University, Taipei, Republic of China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't