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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1995-4-12
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pubmed:abstractText |
In patient tumour samples the activity in vitro of Taxol corresponded fairly well to the known clinical activity and Taxol showed low cross-resistance to standard cytotoxic drugs. However, the Taxol solvent Cremophor EL--ethanol was considerably active alone, whereas paclitaxel formulated in ethanol was less active. Taxol thus seems to contain two components active against patient tumour cells in vitro.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-1341718,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-1357110,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-1361079,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-1363199,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-1434793,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-1677827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-1683908,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-1730510,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-2223576,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-2893642,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-4851371,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-6184155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-7915908,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-8094466,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-8105099,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-8145280,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-8172809,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-8184491,
http://linkedlifedata.com/resource/pubmed/commentcorrection/7880727-8314348
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0007-0920
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
N
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pubmed:pagination |
478-81
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:7880727-Antineoplastic Agents,
pubmed-meshheading:7880727-Drug Screening Assays, Antitumor,
pubmed-meshheading:7880727-Drug Synergism,
pubmed-meshheading:7880727-Fluorometry,
pubmed-meshheading:7880727-Glycerol,
pubmed-meshheading:7880727-Humans,
pubmed-meshheading:7880727-Kinetics,
pubmed-meshheading:7880727-Neoplasms,
pubmed-meshheading:7880727-Paclitaxel,
pubmed-meshheading:7880727-Solvents,
pubmed-meshheading:7880727-Tumor Cells, Cultured
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pubmed:year |
1995
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pubmed:articleTitle |
The cytotoxic activity of Taxol in primary cultures of tumour cells from patients is partly mediated by Cremophor EL.
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pubmed:affiliation |
Department of Oncology, University Hospital, Uppsala University, Sweden.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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