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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
14
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pubmed:dateCreated |
1995-4-6
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pubmed:abstractText |
A specific point mutation in the gene coding for coagulation factor V is associated with resistance to degradation by activated protein C, a recently described abnormality of coagulation that may be associated with an increased risk of venous thrombosis. Whether this mutation also predisposes patients to arterial thrombosis is unknown, as is the value of screening for the mutation in order to define the risk of venous thrombosis among unselected healthy people.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0028-4793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
6
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pubmed:volume |
332
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
912-7
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pubmed:dateRevised |
2010-3-24
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pubmed:meshHeading |
pubmed-meshheading:7877648-Aged,
pubmed-meshheading:7877648-Base Sequence,
pubmed-meshheading:7877648-Cerebrovascular Disorders,
pubmed-meshheading:7877648-Confidence Intervals,
pubmed-meshheading:7877648-Factor V,
pubmed-meshheading:7877648-Follow-Up Studies,
pubmed-meshheading:7877648-Genetic Markers,
pubmed-meshheading:7877648-Genetic Predisposition to Disease,
pubmed-meshheading:7877648-Humans,
pubmed-meshheading:7877648-Male,
pubmed-meshheading:7877648-Molecular Sequence Data,
pubmed-meshheading:7877648-Myocardial Infarction,
pubmed-meshheading:7877648-Point Mutation,
pubmed-meshheading:7877648-Prospective Studies,
pubmed-meshheading:7877648-Pulmonary Embolism,
pubmed-meshheading:7877648-Risk,
pubmed-meshheading:7877648-Thrombophlebitis
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pubmed:year |
1995
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pubmed:articleTitle |
Mutation in the gene coding for coagulation factor V and the risk of myocardial infarction, stroke, and venous thrombosis in apparently healthy men.
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pubmed:affiliation |
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215-1204.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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