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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1995-4-5
|
| pubmed:abstractText |
1. The effects of leg muscle pumping (tiptoeing) and tensing (leg-crossing) on orthostatic blood pressure were investigated in six healthy adult subjects (aged 28-34 years) and in seven patients with severe hypoadrenergic orthostatic hypotension (aged 20-65 years). 2. Finger arterial pressure was monitored. Relative changes in left ventricular stroke volume were computed by a pulse contour method. 3. Tiptoeing increased mean arterial pressure (7 +/- 5 mmHg) in the healthy subjects, but not in the patients, whereas cardiac output increased in both groups, although by more in the healthy adults than in the patients (35 +/- 10% versus 20 +/- 11%, P < 0.05). Systemic vascular resistance decreased substantially in both groups while tiptoeing. Leg-crossing did not affect arterial pressure in the healthy subjects, although stroke volume had increased. In contrast, in the patients an increase in cardiac output (16 +/- 12%) and mean blood pressure (13 +/- 13 mmHg) was observed. 4. Tiptoeing and leg-crossing have different effects on orthostatic blood pressure in healthy adult subjects and in patients with autonomic failure. In normal humans, tiptoeing increases arterial pressure, whereas leg-crossing has little effect. In the patients, in contrast, tiptoeing has little effect, whereas leg-crossing increases arterial pressure considerably. Patients with autonomic failure should be instructed to apply leg-crossing to combat orthostatic dizziness.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0143-5221
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
87
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
553-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:7874844-Adult,
pubmed-meshheading:7874844-Aged,
pubmed-meshheading:7874844-Autonomic Nervous System Diseases,
pubmed-meshheading:7874844-Blood Pressure,
pubmed-meshheading:7874844-Cardiac Output,
pubmed-meshheading:7874844-Female,
pubmed-meshheading:7874844-Heart Rate,
pubmed-meshheading:7874844-Humans,
pubmed-meshheading:7874844-Hypotension, Orthostatic,
pubmed-meshheading:7874844-Leg,
pubmed-meshheading:7874844-Male,
pubmed-meshheading:7874844-Middle Aged,
pubmed-meshheading:7874844-Muscle, Skeletal,
pubmed-meshheading:7874844-Muscle Contraction,
pubmed-meshheading:7874844-Stroke Volume,
pubmed-meshheading:7874844-Supine Position
|
| pubmed:year |
1994
|
| pubmed:articleTitle |
Effects of leg muscle pumping and tensing on orthostatic arterial pressure: a study in normal subjects and patients with autonomic failure.
|
| pubmed:affiliation |
Department of Medicine, Academic Medical Centre, Amsterdam, The Netherlands.
|
| pubmed:publicationType |
Journal Article
|