Linked Life Data

7873099

Source:http://linkedlifedata.com/resource/pubmed/id/7873099

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-3-31
pubmed:abstractText
Salmonella species penetrate (invade) and proliferate within non-phagocytic cells such as epithelial cells. These two processes are essential for Salmonella virulence and have been shown to occur in the intestinal epithelium and cultured epithelial cells. In recent years the signals that Salmonella transmits to the epithelial cell have begun to be elucidated. In this review, we summarize the most recent findings about the molecular nature of the interactions between Salmonella and epithelial cells. These studies reveal that Salmonella causes dramatic changes in the morphology of the host plasma membrane during bacterial invasion, and that this pathogen exploits other host structures such as actin filaments and lysosomes to trigger internalization and intracellular proliferation within non-phagocytic cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0213-4101
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
229-38
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Invasion and intracellular proliferation of Salmonella within non-phagocytic cells.
pubmed:affiliation
Biotechnology Laboratory, University of British Columbia, Canada.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't