Linked Life Data

7870008

Source:http://linkedlifedata.com/resource/pubmed/id/7870008

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
1995-3-24
pubmed:abstractText
Six children aged between three and six years, born from undamaged families and free from malformative, chronic, degenerative or metabolic diseases, never treated with chemoantibiotics, were checked for their immune status. They were compared with other six children with the same somatic characteristics, the same health status and the same economical-social condition as the first six ones; but frequently treated with chemoantibiotics (not less than three therapy periods during each year of their life). The comparative study was performed by checking various parameters (lymphocyte blastization; rosette "E"; T3, T4, T8 lymphocytes with T4/T8 ratio; B lymphocytes; NK cells, chemotaxis; phagocytosis; killing; serum immunoglobulins A, G, M; C3; C4) index of immune functions, in uniform conditions. Results were statistically elaborated by means of "t-Student between groups test", "on ordinal ranks test", "t-Student for paired data test" and "Pearson's correlation coefficient" calculation. Significative differences by means of "t-Student between groups test" were recorded for what C3 is concerned, higher in never treated children, for PWM stimulation Blastization, lower in never treated children, for unstimulated blastization, chemotaxis and plasma IgM lower in frequently treated children. By means of "t-Student for paired data test" the above mentioned differences were confirmed and significantly higher values of plasma Immunoglobulin G and B lymphocyte in never treated children were pointed out. The differences between the last children and the controls are much higher than those previously recorded between similar groups 6-12 years old.
pubmed:language
ita
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0026-4946
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
481-500
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
[Evaluation of the immune status of children never treated wtih chemoantibiotics (children 3 to 6 years old)].
pubmed:affiliation
Istituto di Pediatria, Università degli Studi di Milano.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, English Abstract, Controlled Clinical Trial, Research Support, Non-U.S. Gov't