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rdf:type |
|
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lifeskim:mentions |
umls-concept:C0036025,
umls-concept:C0040915,
umls-concept:C0449432,
umls-concept:C0678933,
umls-concept:C0683598,
umls-concept:C1179435,
umls-concept:C1283195,
umls-concept:C1524073,
umls-concept:C1548799,
umls-concept:C1705248,
umls-concept:C1711351
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pubmed:issue |
4
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pubmed:dateCreated |
1976-12-3
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pubmed:abstractText |
Resistance to the protein synthesis inhibitor trichodermin in Saccharomyces cerevisiae has been studied. A single recessive nuclear gene was responsible for resistance. The resistance locus, tcm1 was found to be closely linked (1 centi-morgan) to the locus pet 17 on the right arm of chromosome XV. The mutation to trichodermin resistance conferred resistance to other 12,13-epoxytrichothecenes and to the structurally unrelated antibiotic anisomycin.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0016-6731
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
83
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
|
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pubmed:pagination |
667-73
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:786781-Anisomycin,
pubmed-meshheading:786781-Chromosomes,
pubmed-meshheading:786781-Drug Resistance, Microbial,
pubmed-meshheading:786781-Genes, Recessive,
pubmed-meshheading:786781-Genetic Linkage,
pubmed-meshheading:786781-Mutation,
pubmed-meshheading:786781-Saccharomyces cerevisiae,
pubmed-meshheading:786781-Sesquiterpenes,
pubmed-meshheading:786781-Trichodermin
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|
pubmed:year |
1976
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|
pubmed:articleTitle |
Mapping of trichodermin resistance in Saccharomyces cerevisiae: a genetic locus for a component of the 60S ribsomal subunit.
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|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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