rdf:type |
|
lifeskim:mentions |
umls-concept:C0009368,
umls-concept:C0012984,
umls-concept:C0020885,
umls-concept:C0205263,
umls-concept:C0231491,
umls-concept:C0243192,
umls-concept:C0330390,
umls-concept:C0442805,
umls-concept:C0597357,
umls-concept:C0602375,
umls-concept:C1140999,
umls-concept:C1533157,
umls-concept:C2347318
|
pubmed:issue |
5
|
pubmed:dateCreated |
1995-3-30
|
pubmed:abstractText |
The regulatory roles of tachykinins in intestinal motor function may be clarified by use of novel, stable and selective antagonists of neurokinin receptors. We studied the effects of the non-peptide NK-2 receptor antagonist SR48968 on canine colonic tone under resting conditions and after stimulation by the selective NK-2 receptor agonist [beta Ala8] neurokinin A-(4-10).
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0269-2813
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
527-33
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7865645-Animals,
pubmed-meshheading:7865645-Benzamides,
pubmed-meshheading:7865645-Colon,
pubmed-meshheading:7865645-Dogs,
pubmed-meshheading:7865645-Female,
pubmed-meshheading:7865645-Gastrointestinal Motility,
pubmed-meshheading:7865645-Ileum,
pubmed-meshheading:7865645-Muscle, Smooth,
pubmed-meshheading:7865645-Muscle Contraction,
pubmed-meshheading:7865645-Neurokinin A,
pubmed-meshheading:7865645-Peptide Fragments,
pubmed-meshheading:7865645-Piperidines,
pubmed-meshheading:7865645-Receptors, Neurokinin-2
|
pubmed:year |
1994
|
pubmed:articleTitle |
A selective NK-2 antagonist blocks the increase of canine colonic tone and ileal contractions induced by the NK-2 selective receptor agonist, [beta Ala8] neurokinin A-(4-10).
|
pubmed:affiliation |
Gastroenterology Research Unit, Mayo Clinic, Rochester, MN 55903.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|