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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1995-3-20
|
| pubmed:abstractText |
While gonadotropin-releasing hormone (GnRH), GnRH-like, or GnRH receptor (GnRH-R) have been reported to exist in several tissues other than brain or anterior pituitary, there is no report concerning GnRH or GnRH-R gene expression in the normal mammary gland. In order to define the production of GnRH as well as GnRH-R in the mammary gland at the molecular level we examined their gene expression in various functional stages of the mouse mammary gland using the reverse transcriptase-polymerase chain reaction (RT-PCR). GnRH mRNA transcripts were found in mouse mammary glands of mid-pregnant, lactating, and 3, 6, 9 days post-lactational mice, whereas GnRH-R mRNA transcripts were not detected in mammary glands of any functional stage. These results suggest a possible biological role of GnRH in mammary gland.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0006-291X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
207
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
800-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:7864875-Animals,
pubmed-meshheading:7864875-Base Sequence,
pubmed-meshheading:7864875-DNA Primers,
pubmed-meshheading:7864875-Electrophoresis, Agar Gel,
pubmed-meshheading:7864875-Female,
pubmed-meshheading:7864875-Gene Expression,
pubmed-meshheading:7864875-Gonadotropin-Releasing Hormone,
pubmed-meshheading:7864875-Lactation,
pubmed-meshheading:7864875-Mammary Glands, Animal,
pubmed-meshheading:7864875-Mice,
pubmed-meshheading:7864875-Mice, Inbred BALB C,
pubmed-meshheading:7864875-Mice, Inbred C3H,
pubmed-meshheading:7864875-Molecular Sequence Data,
pubmed-meshheading:7864875-Polymerase Chain Reaction,
pubmed-meshheading:7864875-Pregnancy,
pubmed-meshheading:7864875-RNA, Messenger,
pubmed-meshheading:7864875-Receptors, LHRH,
pubmed-meshheading:7864875-Transcription, Genetic
|
| pubmed:year |
1995
|
| pubmed:articleTitle |
Detection of messenger RNA for gonadotropin-releasing hormone (GnRH) but not for GnRH receptors in mouse mammary glands.
|
| pubmed:affiliation |
Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|