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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-3-21
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pubmed:abstractText |
The changes in MR-determined synovial membrane volume, early synovial enhancement, and cartilage and bone erosions after osmic acid knee synovectomy were studied. Gadolinium-DTPA enhanced magnetic resonance imaging (MRI) of 18 knees with persistent arthritis was performed before and 1 month after treatment. The synovial membrane volume was significantly reduced (median -52%) in all 9 patients brought into clinical remission (p < 0.01), while no significant change was found in patients with clinical relapse. The early synovial enhancement was not significantly changed. MRI revealed progressive erosive changes in 2 patients. The time of relapse was correlated to a MR-erosion score, but not to early synovial enhancement or volumes of synovium or effusion (Spearman tests). MRI-determined synovial membrane volumes and early synovial enhancement may be objective quantitative markers of inflammation. MR-scores of cartilage and bone erosions are sensitive to progressive changes occurring within a month.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-9742
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
5-12
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7863280-Adult,
pubmed-meshheading:7863280-Aged,
pubmed-meshheading:7863280-Bone and Bones,
pubmed-meshheading:7863280-Cartilage,
pubmed-meshheading:7863280-Humans,
pubmed-meshheading:7863280-Injections, Intra-Articular,
pubmed-meshheading:7863280-Knee Joint,
pubmed-meshheading:7863280-Magnetic Resonance Imaging,
pubmed-meshheading:7863280-Middle Aged,
pubmed-meshheading:7863280-Osmium Tetroxide,
pubmed-meshheading:7863280-Recurrence,
pubmed-meshheading:7863280-Synovial Membrane,
pubmed-meshheading:7863280-Synovitis,
pubmed-meshheading:7863280-Time Factors
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pubmed:year |
1995
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pubmed:articleTitle |
Effect of intraarticular osmic acid on synovial membrane volume and inflammation, determined by magnetic resonance imaging.
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pubmed:affiliation |
Danish Research Center of Magnetic Resonance, Hvidovre Hospital, University of Copenhagen.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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