Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1976-11-1
|
| pubmed:abstractText |
The mutagenicity of halothane was tested in an in-vitro microbial assay system employing two histidine-dependent mutants of Salmonella typhimurium, TA98 and TA100, Halothane in concentrations ranging from 0.1 to 30 per cent was incubated with bacteria in the presence or absence of a metabolic activation system prepared from either rat liver treated with Aroclor 1254 or human liver. Trifluoroacetic acid, a major metabolite of halothane, and urine from patients anesthetized with halothane also were tested. Halothane, trifluoroacetic acid, and patients' urines were not mutagenic.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Sep
|
| pubmed:issn |
0003-3022
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
45
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
311-8
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:786079-Aminobiphenyl Compounds,
pubmed-meshheading:786079-Anesthesia, Inhalation,
pubmed-meshheading:786079-Animals,
pubmed-meshheading:786079-Dichloroethylenes,
pubmed-meshheading:786079-Genetics, Microbial,
pubmed-meshheading:786079-Halothane,
pubmed-meshheading:786079-Humans,
pubmed-meshheading:786079-Male,
pubmed-meshheading:786079-Mutation,
pubmed-meshheading:786079-Rats,
pubmed-meshheading:786079-Salmonella typhimurium
|
| pubmed:year |
1976
|
| pubmed:articleTitle |
Mutagenicity of volatile anesthetics: halothane.
|
| pubmed:publicationType |
Journal Article
|