Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1995-3-23
|
pubmed:abstractText |
Scid mice are severely immunodeficient as a result of a defective recombinase system. Mice with the scid mutation have been shown to have an increased sensitivity to ionizing radiation, presumably as a result of an inability to repair DNA damage. Little is known of the impact of this mutation on the thermal response and on hyperthermic radiosensitization. This investigation established the thermal response (42-44 degrees C), patterns of thermotolerance development, and the impact of hyperthermia (60 min at 40 degrees C or 42 degrees C) on the radiation response of bone marrow colony forming unit-culture cells (CFU-C) in scid mice.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0360-3016
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
905-10
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:7860404-Animals,
pubmed-meshheading:7860404-Bone Marrow,
pubmed-meshheading:7860404-Bone Marrow Cells,
pubmed-meshheading:7860404-Cell Survival,
pubmed-meshheading:7860404-Colony-Forming Units Assay,
pubmed-meshheading:7860404-Dose-Response Relationship, Drug,
pubmed-meshheading:7860404-Hyperthermia, Induced,
pubmed-meshheading:7860404-Mice,
pubmed-meshheading:7860404-Mice, SCID,
pubmed-meshheading:7860404-Radiation Tolerance
|
pubmed:year |
1995
|
pubmed:articleTitle |
Thermal response and hyperthermic radiosensitization of scid mouse bone marrow CFU-C.
|
pubmed:affiliation |
Department of Radiation Oncology and Nuclear Medicine, Thomas Jefferson University, Philadelphia, PA 19107-5097.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|