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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1995-3-16
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pubmed:abstractText |
Between July 89 and June 92, 70 patients with primary hyperparathyroidism underwent adenomectomy by unilateral incision under local anesthesia (Ul/LA), without exploration of the remaining glands. The procedure was carried out with intraoperative monitoring of urinary cyclic AMP (n = 35), Calcemia was measured 6-monthly for one year in every patient. 62 (88.6%) patients were cured after Ul/LA, whereas 5 patients required conversion to bilateral cervicotomy under general anesthesia because of abnormal hormonal levels, thus giving an overall success rate of 97% (67/70). The reasons for treatment failure of Ul/LA included misleading conclusions of cervical ultrasonography (n = 5), agitation of the patient (n = 1) and deep localization of the adenoma (n = 1). When cervical ultrasonography is suggestive of a parathyroid adenoma in expert hands, the probability of a second localization or associated hyperplasia is very low, so that adenomectomy by Ul/LA can be attempted safely, provided that the serum level of intact parathyroid hormone returns to normal values within one hour following resection. In our experience, parathyroidectomy by Ul/LA should not be considered in case of non conclusive ultrasonography, familial history pf hyperparathyroidism of MEN-I, ultrasonic evidence of several enlarged glands or associated thyroid nodule requiring simultaneous treatment.
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pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0003-4266
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
171-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7857082-Adult,
pubmed-meshheading:7857082-Aged,
pubmed-meshheading:7857082-Aged, 80 and over,
pubmed-meshheading:7857082-Anesthesia, Local,
pubmed-meshheading:7857082-Cyclic AMP,
pubmed-meshheading:7857082-Female,
pubmed-meshheading:7857082-Humans,
pubmed-meshheading:7857082-Hyperparathyroidism,
pubmed-meshheading:7857082-Intraoperative Period,
pubmed-meshheading:7857082-Male,
pubmed-meshheading:7857082-Methods,
pubmed-meshheading:7857082-Middle Aged,
pubmed-meshheading:7857082-Parathyroid Hormone
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pubmed:year |
1994
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pubmed:articleTitle |
[Surgery of primary hyperparathyroidism by unilateral approach under local anesthesia and intraoperative determination of PTH 1-84].
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pubmed:affiliation |
Clinique Chirurgicale, Hôpital Cochin, Paris.
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pubmed:publicationType |
Journal Article,
English Abstract
|