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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1995-3-14
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pubmed:abstractText |
In a series of 120 hypertensive patients, 60 were found to have echocardiographic left ventricular (LV) hypertrophy (Devereux's method). Of these, 18 (30%) had typical stress-induced angina and underwent coronary angiography, which showed that 11 (61%) had normal coronary arteries, and 7 (39%) (p < 0.05) had coronary stenosis of the epicardial arteries. Stress-rest thallium-201 scintigraphy (Burow's quantitative method) yielded abnormal results in 21 of the 60 patients with LV hypertrophy. Five of 30 (17%) were asymptomatic, 14 of 18 (78%) had angina, and 2 of 12 (17%) had dyspnea on exertion. In 5 normal patients used as a control group, coronary flow reserve after administration of papaverine (10 coronary arteries) was 6.25 +/- 1.4 versus 3.7 +/- 0.8 in 10 thallium-negative, asymptomatic hypertensive patients with LV hypertrophy (p < 0.001). The mean coronary flow reserve of 21 patients with abnormal thallium-201 results was 2.71 +/- 0.96 (p < 0.01 compared with the group with normal thallium-201 findings) and 2.5 +/- 0.6 in the segments with lowest uptake (p < 0.05 compared with normal segments in these same patients). Thus, stress-induced angina pectoris in hypertensive patients with LV hypertrophy was due to small-vessel disease in over half of our patients (62%).
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0002-9149
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
335-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:7856523-Adult,
pubmed-meshheading:7856523-Aged,
pubmed-meshheading:7856523-Angina Pectoris,
pubmed-meshheading:7856523-Coronary Vessels,
pubmed-meshheading:7856523-Echocardiography,
pubmed-meshheading:7856523-Exercise Test,
pubmed-meshheading:7856523-Female,
pubmed-meshheading:7856523-Humans,
pubmed-meshheading:7856523-Hypertension,
pubmed-meshheading:7856523-Hypertrophy, Left Ventricular,
pubmed-meshheading:7856523-Male,
pubmed-meshheading:7856523-Microcirculation,
pubmed-meshheading:7856523-Middle Aged,
pubmed-meshheading:7856523-Thallium Radioisotopes
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pubmed:year |
1995
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pubmed:articleTitle |
Microvascular angina pectoris in hypertensive patients with left ventricular hypertrophy and diagnostic value of exercise thallium-201 scintigraphy.
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pubmed:affiliation |
University of the Basque Country, Institute of Cardiology, Hospital Civil de Basurto, Bilbao (Bizkaia), Spain.
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pubmed:publicationType |
Journal Article
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