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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1995-3-16
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pubmed:abstractText |
Interaction between immune cells and tumoral cells of a case of glioblastoma was studied. Tissue fragments obtained during neurosurgery from different areas of the tumor were examined before and after rIL-2 treatment in vitro. The same morphofunctional type of cells usually activated by rIL-2, which show antitumoral reactivity, was observed both in the glioblastoma imprints and in tumoral fragments cultured with rIL-2. This cytokine stimulated the proliferation of tumor infiltrating lymphocytes in vitro. This preliminary study shows that IL-2 potentiates the differentiation of HMS cells in peripheral blood which probably pass through the blood brain barrier and infiltrate the tumor.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0001-6276
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
198-205
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7856474-Aged,
pubmed-meshheading:7856474-Brain Neoplasms,
pubmed-meshheading:7856474-Carcinoma, Bronchogenic,
pubmed-meshheading:7856474-Female,
pubmed-meshheading:7856474-Glioblastoma,
pubmed-meshheading:7856474-Humans,
pubmed-meshheading:7856474-Immunity, Cellular,
pubmed-meshheading:7856474-Interleukin-2,
pubmed-meshheading:7856474-Lung Neoplasms,
pubmed-meshheading:7856474-Lymphocyte Activation,
pubmed-meshheading:7856474-Lymphocytes, Tumor-Infiltrating,
pubmed-meshheading:7856474-Mesothelioma,
pubmed-meshheading:7856474-Recombinant Proteins,
pubmed-meshheading:7856474-Temporal Lobe,
pubmed-meshheading:7856474-Tumor Cells, Cultured,
pubmed-meshheading:7856474-Tumor Markers, Biological
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pubmed:year |
1994
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pubmed:articleTitle |
Activated lymphocytes in glioblastoma: significance for anti-tumoral immunity.
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pubmed:affiliation |
Fond. Istit. Neurol. C. Mondino, Univ. di Pavia.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Case Reports
|