Linked Life Data

7855835

Source:http://linkedlifedata.com/resource/pubmed/id/7855835

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1995-3-15
pubmed:abstractText
One year after heart transplantation, serum total cholesterol had increased by 24% in 103 recipients on prednisolon, cyclosporin A, and azathioprin immuno-suppression, and was above 5.2 mmol/l in 84 of them. Incremental small dose lovastatin treatment up to 20 mg per day safely reduced total cholesterol by 19% and LDL-cholesterol by 24% in 14 patients with serum cholesterol above 7.5 mmol/l. Serum concentration of lovastatin did not increase further after three weeks treatment with 20 mg. It is concluded that hypercholesterolaemia in heart recipients treated with cyclosporin A can be treated safely with small dose lovastatin. Drug therapy should be individualized and conducted by physicians experienced in transplantation medicine.
pubmed:language
nor
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0029-2001
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
357-9
pubmed:dateRevised
2008-7-16
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
[Hypercholesterolemia--a clinical problem in heart transplantation. A therapeutic trial with low-dose lovastatin].
pubmed:affiliation
Medisinsk avdeling B, Rikshospitalet, Oslo.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract, Research Support, Non-U.S. Gov't