Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1995-3-15
|
pubmed:abstractText |
The use of FISH as a complement to the conventional cytogenetic studies is of great help in attaining a better characterisation of the chromosome anomalies present in haematological malignancies, such as chromosome 7 monosomy. A study was carried out in three cases of acute non-lymphoblastic leukaemia and a myelodysplastic syndrome with chromosome 7 involvement, as shown by conventional cytogenetic studies. The Cocktail probe for chromosome 7 (DZ1, DZ2) was used (Oncor) in performing in situ hybridation. A monosomic cell line for chromosome 7, undetected by conventional techniques, was disclosed with this procedure in two of the cases. In the remaining two patients the monosomy of chromosome 7 was confirmed, although at percentages different from those attained with the conventional methods.
|
pubmed:language |
spa
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0036-4355
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
39
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
457-60
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:7855698-Chromosomes, Human, Pair 7,
pubmed-meshheading:7855698-Humans,
pubmed-meshheading:7855698-In Situ Hybridization, Fluorescence,
pubmed-meshheading:7855698-Interphase,
pubmed-meshheading:7855698-Karyotyping,
pubmed-meshheading:7855698-Leukemia, Myeloid, Acute,
pubmed-meshheading:7855698-Myelodysplastic Syndromes
|
pubmed:year |
1994
|
pubmed:articleTitle |
[Interphasic in situ fluorescent hybridization (FISH) in 4 cases of myeloid neoplasias with chromosome 7 changes].
|
pubmed:affiliation |
Departamento de Genética, Fundación Jiménez Díaz, Madrid.
|
pubmed:publicationType |
Journal Article,
English Abstract
|