Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1995-3-15
pubmed:abstractText
9-Methoxytariacuripyrone, a nitro-aromatic compound isolated from Aristolochia brevipes showed strong mutagenic activity in strain TA98, TA100 and some YG strains of Salmonella typhimurium with and without S9 mix. Incubation with cytosol resulted in a heavy increase in mutagenicity. When incubated with microsomes the activity was dramatically decreased. The results are discussed in view of the enzymes possibly involved in activation and detoxification of the compound. The role of the basic structure on the mutagenicity mediated through the nitro group was also considered.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0267-8357
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
547-51
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
9-Methoxytariacuripyrone, a naturally occurring nitro-aromatic compound with strong mutagenicity in Salmonella typhimurium.
pubmed:affiliation
Institut für Botanik und Pharmazeutische Biologie der Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany.
pubmed:publicationType
Journal Article