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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1995-3-16
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pubmed:databankReference |
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pubmed:abstractText |
Several outbreaks of Group C rotavirus infection have occurred in the United Kingdom, in one instance infection was associated with the death of a 4-month-old infant in the Bristol area. The origin of human group C rotavirus is unknown although there has been some speculation that porcine species may be a possible source of human infection. Direct reverse transcription-polymerase chain reaction sequencing of VP7 genes from two UK outbreaks (Bristol and Preston) and sequence analysis from a sporadic case of infection from Brazil (Belém) showed that each of these genes was identical in size (1,063 bp) and has revealed a surprising level (97.8-99.8%) of gene sequence conservation. Sequence comparisons with an isolate from Japan imply that the human group C rotaviruses so far characterised originate from a recent common ancestor with a worldwide distribution.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0146-6615
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:geneSymbol |
VP7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
166-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7852957-Amino Acid Sequence,
pubmed-meshheading:7852957-Antigens, Viral,
pubmed-meshheading:7852957-Base Sequence,
pubmed-meshheading:7852957-Capsid,
pubmed-meshheading:7852957-Capsid Proteins,
pubmed-meshheading:7852957-Conserved Sequence,
pubmed-meshheading:7852957-DNA, Complementary,
pubmed-meshheading:7852957-DNA, Viral,
pubmed-meshheading:7852957-DNA Primers,
pubmed-meshheading:7852957-Disease Outbreaks,
pubmed-meshheading:7852957-Gastroenteritis,
pubmed-meshheading:7852957-Genes, Viral,
pubmed-meshheading:7852957-Great Britain,
pubmed-meshheading:7852957-Humans,
pubmed-meshheading:7852957-Infant,
pubmed-meshheading:7852957-Molecular Sequence Data,
pubmed-meshheading:7852957-Polymerase Chain Reaction,
pubmed-meshheading:7852957-Rotavirus,
pubmed-meshheading:7852957-Rotavirus Infections,
pubmed-meshheading:7852957-Sequence Homology, Amino Acid,
pubmed-meshheading:7852957-Sequence Homology, Nucleic Acid
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pubmed:year |
1994
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pubmed:articleTitle |
Sequence conservation of the major outer capsid glycoprotein of human group C rotaviruses.
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pubmed:affiliation |
Department of Molecular Microbiology, University Medical School, Southampton General Hospital, United Kingdom.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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