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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1976-10-20
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pubmed:abstractText |
Sodium nalidixate inhibited the cell growth and division of several respiratory competent strains of Saccharomyces cerevisiae. A number of cytoplasmic petite strains (both spontaneous and induced by ethidium bromide) were shown to be more resistant to sodium nalidixate than the wild-type strains from which they were derived. There was considerable variation in sensitivity of different petites derived from the same wild-type. Usually petite strains which were induced by ethidium bromide were more resistant than spontaneously arising petites. The susceptibility of a wild-type strain to nalidixate was found to be least when the mitochondrial respiratory system was maximally repressed. It was also noted that sodium nalidixate (100 mug/ml) induced petite mutants.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0026-8925
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
5
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pubmed:volume |
146
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
95-100
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pubmed:dateRevised |
2000-12-18
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pubmed:meshHeading |
pubmed-meshheading:785214-Cell Division,
pubmed-meshheading:785214-Drug Resistance, Microbial,
pubmed-meshheading:785214-Ethidium,
pubmed-meshheading:785214-Mutation,
pubmed-meshheading:785214-Nalidixic Acid,
pubmed-meshheading:785214-Saccharomyces cerevisiae,
pubmed-meshheading:785214-Species Specificity
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pubmed:year |
1976
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pubmed:articleTitle |
Differential effects of nalidixate on the cell growth of respiratory competent strains and cytoplasmic petite mutants of Saccharomyces cerevisiae.
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pubmed:publicationType |
Journal Article
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