|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017890,
umls-concept:C0019046,
umls-concept:C0030946,
umls-concept:C0038170,
umls-concept:C0086418,
umls-concept:C0205419,
umls-concept:C0294156,
umls-concept:C0678594,
umls-concept:C0680730,
umls-concept:C1148554,
umls-concept:C1524063,
umls-concept:C1707959,
umls-concept:C2003941
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|
pubmed:issue |
4-5
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|
pubmed:dateCreated |
1995-3-14
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|
pubmed:abstractText |
In human hemoglobin, enzymic cleavage with the protease from Staphylococcus aureus strain V8 (protease V8) is a convenient method for the study of variants that involve large peptides such as alpha T-9 and alpha T-12b. We report here on Hb Valparaiso [alpha 88(F9)Ala-->Gly], a new neutral variant with a slight increase in oxygen affinity, that was identified by use of this strategy.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0363-0269
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
18
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
275-84
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:7852082-Female,
pubmed-meshheading:7852082-Globins,
pubmed-meshheading:7852082-Hemoglobins, Abnormal,
pubmed-meshheading:7852082-Humans,
pubmed-meshheading:7852082-Infant,
pubmed-meshheading:7852082-Oxygen,
pubmed-meshheading:7852082-Oxyhemoglobins,
pubmed-meshheading:7852082-Peptide Mapping,
pubmed-meshheading:7852082-Protein Conformation,
pubmed-meshheading:7852082-Sequence Analysis,
pubmed-meshheading:7852082-Serine Endopeptidases
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|
pubmed:year |
1994
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|
pubmed:articleTitle |
The use of Staphylococcus V8 protease in the structural determination of human hemoglobin variants: HB Valparaiso [alpha 88(F9)Ala-->Gly] example.
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pubmed:affiliation |
INSERM U299, Hôpital de Bicetre, Le Kremlin-Bicêtre, France.
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pubmed:publicationType |
Journal Article,
Case Reports
|
