Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10-11
pubmed:dateCreated
1995-3-10
pubmed:abstractText
Attachment of mammalian embryos to the uterine wall involves the coordinated development of both the embryo and the uterine epithelium to an attachment-competent state. This coordination is achieved directly or indirectly through the actions of ovarian steroids. Acquisition of attachment competence is proposed to reflect two processes. The first is the loss of non-adhesive glycoproteins at the cell surface of embryos, e.g. zona pellucida subunits, as well as uterine epithelial cells, e.g. mucin glycoproteins. The second process is the functional expression of complementary adhesion-promoting molecules at these cell surfaces. A series of studies indicates that heparan sulfate proteoglycans and their corresponding binding sites can play an important role in the initial stage of embryo attachment to the uterine surface.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0020-711X
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1269-77
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:articleTitle
Cell surface glycoconjugates as modulators of embryo attachment to uterine epithelial cells.
pubmed:affiliation
Department of Biochemistry and Molecular Biology, M.D. Anderson Cancer Center, Houston, TX 77030.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't