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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1995-3-14
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pubmed:abstractText |
In this study the long-term prognosis was analysed of all 462 consecutive female breast cancer patients who were diagnosed and carefully staged between 1970 and 1980 in a 600-bed community hospital in Eindhoven, south east Netherlands. Follow-up of recurrence and causes of death was obtained until 1 January 1993. Observed survival rates at 5, 10 and 20 years were 66%, 45% and 32%, respectively, and the corresponding breast cancer-specific survival rates were 71%, 54% and 44%. The yearly risk for a recurrence of breast cancer after treatment steadily decreased from 10% the first year to 1% after 10 years. In a multivariate survival analysis both tumour size and nodal status appeared to be equally important prognostic factors in the first 5 years after diagnosis. After 5 years only tumour size had independent prognostic value, which was not significant any more after 10 years. In patients with a tumour size < or = 2 cm and without lymph node involvement at diagnosis, the risk for a recurrence was found to be negligible after 10 years. Those patients may be considered cured, although a search for early diagnosis of a second primary breast cancer in this group is still advisable.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0748-7983
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
42-6
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pubmed:dateRevised |
2007-7-2
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pubmed:meshHeading |
pubmed-meshheading:7851551-Adult,
pubmed-meshheading:7851551-Age Factors,
pubmed-meshheading:7851551-Aged,
pubmed-meshheading:7851551-Aged, 80 and over,
pubmed-meshheading:7851551-Breast Neoplasms,
pubmed-meshheading:7851551-Female,
pubmed-meshheading:7851551-Follow-Up Studies,
pubmed-meshheading:7851551-Hospitals, General,
pubmed-meshheading:7851551-Humans,
pubmed-meshheading:7851551-Lymphatic Metastasis,
pubmed-meshheading:7851551-Middle Aged,
pubmed-meshheading:7851551-Neoplasm Staging,
pubmed-meshheading:7851551-Netherlands,
pubmed-meshheading:7851551-Predictive Value of Tests,
pubmed-meshheading:7851551-Prognosis,
pubmed-meshheading:7851551-Survival Rate,
pubmed-meshheading:7851551-Time Factors
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pubmed:year |
1995
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pubmed:articleTitle |
Long-term prognosis of breast cancer: an analysis of 462 patients in a general hospital in south east Netherlands.
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pubmed:affiliation |
Comprehensive Cancer Center South, Eindhoven, The Netherlands.
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pubmed:publicationType |
Journal Article
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