Linked Life Data

7848520

Source:http://linkedlifedata.com/resource/pubmed/id/7848520

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1995-3-16
pubmed:abstractText
The survival and death of lymphoid cells is under the control of a genetic program. Cell death is activated at different stages of development and serves to remove unnecessary and autoreactive lymphocytes, as well as to limit the immune response. The survival of cells is regulated by a set of genes that act as repressors of the cell death mechanism. Of these, bcl-2 and bcl-x exhibit a striking pattern of regulation during lymphoid maturation and can inhibit several forms of apoptotic cell death. Here, Gabriel Núñez and colleagues review recent developments in the field, particularly focusing on the role of the Bcl-2 and Bcl-x proteins in regulating lymphoid death and survival.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0167-5699
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
582-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1994
pubmed:articleTitle
Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival.
pubmed:affiliation
Dept of Pathology, University of Michigan, Ann Arbor 48109.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't