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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1995-3-9
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pubmed:abstractText |
We report the case of an elderly woman with a history of headache, vomiting and dizziness while walking. On CT scans a mass was identified in the right cerebellar hemisphere exhibiting radiological characteristics of lipomatous tissue. Surgery revealed a compact lesion consisting of whitish-yellow tissue with a fatty aspect and texture. Smears of tissue samples and paraffin sections showed features suggestive of tissue mainly composed of fully differentiated lipocytes. Lipid-specific stainings on fresh frozen material confirmed univacuolar intracytoplasmic fat accumulation. However, immunohistochemistry for glial fibrillary acidic protein and electron microscopy clearly demonstrated the glial lineage of these lipid-laden cells. Therefore, the tumor was diagnosed as a highly lipidized astrocytoma. In our view, this case represents a variant of lipidized gliomas that has not been described previously and that differs phenotypically from the entities documented earlier.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-6322
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
485-9
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pubmed:dateRevised |
2007-11-9
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pubmed:meshHeading |
pubmed-meshheading:7847080-Adipose Tissue,
pubmed-meshheading:7847080-Aged,
pubmed-meshheading:7847080-Astrocytoma,
pubmed-meshheading:7847080-Cerebellar Neoplasms,
pubmed-meshheading:7847080-Female,
pubmed-meshheading:7847080-Glioma,
pubmed-meshheading:7847080-Humans,
pubmed-meshheading:7847080-Immunohistochemistry,
pubmed-meshheading:7847080-Tomography, X-Ray Computed
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pubmed:year |
1994
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pubmed:articleTitle |
Cerebellar astrocytoma with extensive lipidization mimicking adipose tissue.
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pubmed:affiliation |
Department of Pathology, Academic Medical Centre, Amsterdam, The Netherlands.
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pubmed:publicationType |
Journal Article,
Case Reports
|