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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
19-20
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pubmed:dateCreated |
1995-3-9
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pubmed:abstractText |
In this paper statistical methods are proposed to estimate the distribution of a CD4 T-cell number at the time of a clinical AIDS endpoint from serial measurements of CD4 T-cell values in a cohort study. The statistical formulation of the problem is that of survival analysis with interval censored data, but in which the endpoints are obtained with measurement error. A measurement error likelihood is developed, assuming normality of the CD4 distribution at AIDS. A maximum likelihood estimation procedure and a Gibbs sampling approach are implemented.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0277-6715
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2059-66
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:7846410-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:7846410-Bias (Epidemiology),
pubmed-meshheading:7846410-CD4-Positive T-Lymphocytes,
pubmed-meshheading:7846410-Cohort Studies,
pubmed-meshheading:7846410-HIV Infections,
pubmed-meshheading:7846410-Homosexuality, Male,
pubmed-meshheading:7846410-Humans,
pubmed-meshheading:7846410-Likelihood Functions,
pubmed-meshheading:7846410-Los Angeles,
pubmed-meshheading:7846410-Male,
pubmed-meshheading:7846410-Models, Statistical,
pubmed-meshheading:7846410-Survival Analysis,
pubmed-meshheading:7846410-Time Factors
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pubmed:articleTitle |
Marker values at the time of an AIDS diagnosis.
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pubmed:affiliation |
Department of Biostatistics, University of California, Los Angeles 90024-1772.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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